Dr. Rajesh Kanna Gopal

I have eight years of research experience in the field of Algal Biotechnology (Marine macroalgae, isolation and culturing microalgae). At present, I am working on antiviral and anti-arthritic potential of bioactive compounds, industrial and domestic wastewater Phycoremediation, alcoholic beverages, and bioplastic from macroalgae (Seaweed); Non-ribosomal polypeptides and Exopolysaccharides from cyanobacteria, LDPE degradation by microalgae.

EDUCATION

• PhD: Plant Biology and Plant Biotechnology, Thesis entitled: Isolation, Purification and Characterization of Superoxide dismutase (SOD) enzyme from Microalgae – 2014-2019, University of Madras, Chennai, Tamil Nadu, India.
• M.Phil.: Botany, Dissertation entitled: Studies on the Detection, Production and Analysis of Cholesterol Oxidase from Stenotrophomonas sp. – 2011-2012, GPA: 7.8, University of Madras, Chennai, Tamil Nadu, India.
• M.Sc.: Plant Biology and Plant Biotechnology – 2009-2011, GPA: 8.19, University of Madras, Chennai, Tamil Nadu, India.
• B.Sc.: Plant Biology and Plant Biotechnology – 2006-2009, GPA: 7.2 University of Madras, Chennai, Tamil Nadu, India.

RESEARCH, TEACHING, or OTHER INTERESTS

Biotechnology, Medicine, Dentistry

Scopus Publications

Letter to the Editor Regarding the Article “PTV Margins in MR-guided and Beam-gated SBRT of Liver Metastases: GTV Dose Escalation Can Reduce the Required PTV”
A. Viswanathan, P.S. Ganesh, and R.K. Gopal
Elsevier BV



Mpox vaccination strategies in DR Congo
Rajesh Kanna Gopal, Pitchaipillai Sankar Ganesh, and Naji Naseef Pathoor
Elsevier BV



Enhancing microbiome-based biomarkers: challenges and opportunities
Rajesh Kanna Gopal, Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, and Akshaya Viswanathan
Elsevier BV



Letter to the Editor Regarding the Article “Effective Strategies for the Prevention and Mitigation of Phosphatidylinositol-3-Kinase Inhibitor-Associated Hyperglycemia: Optimizing Patient Care”
Akshaya viswanathan, Rajesh Kanna Gopal, and Pitchaipillai Sankar Ganesh
Elsevier BV



Reflection on Transoral Robotic Surgery vs Transoral Laser Microsurgery in HPV-Positive Oropharyngeal Squamous Cell Carcinoma
Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, and Rajesh Kanna Gopal
American Medical Association (AMA)



3-Hydroxybenzoic acid inhibits the virulence attributes and disrupts biofilm production in clinical isolates of Acinetobacterbaumannii
N. Pathoor, P. Ganesh, Abdul R Anshad, Rajesh Kanna Gopal, Esaki Muthu Ponmalar, Suvaiyarasan Suvaithenamudhan, Parthiban Rudrapathy and E. M. Shankar




Letter to the editor regarding “Influenza vaccination and COVID-19 infection risk and disease severity: A systematic review and multilevel meta-analysis of prospective studies”
P. Ganesh, N. Pathoor, Rajesh Kanna Gopal, Akshaya Viswanathan and E. M. Shankar




Letter to the Editor Regarding the Article “The Impact of COVID-19 on Breast Cancer Care: A Qualitative Analysis of Surgeons’ Perspectives”
Akshaya viswanathan, Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, and Rajesh Kanna Gopal
Elsevier BV



Correspondence to the Editor: Performance of Multimodal Artificial Intelligence Chatbots Evaluated on Clinical Oncology Cases
R.K. Gopal, P. Sankar Ganesh, and N.N. Pathoor
Elsevier BV



Functional antibody responses associated with effectiveness of RTS,S malaria vaccine in children: new insights and implications
Rajesh Kanna Gopal, Pitchaipillai Sankar Ganesh, and Naji Naseef Pathoor
Elsevier BV



Microbiome interactions: Acinetobacter baumannii biofilms as a co-factor in oral cancer progression
Naji Naseef Pathoor, Pitchaipillai Sankar Ganesh, and Rajesh Kanna Gopal
Springer Science and Business Media LLC



Letter to the Editor regarding the article “Effectiveness and Safety of Pyrotinib-Based Therapy in the Treatment of HER2-Positive Breast Cancer Patients with Brain Metastases: A Multicenter Real-World Study”
Akshaya Viswanathan, Naji Naseef Pathoor, Rajesh Kanna Gopal, and Pitchaipillai Sankar Ganesh
Elsevier BV



Synergistic Interplay of Diet, Gut Microbiota, and Insulin Resistance: Unraveling the Molecular Nexus
Rajesh Kanna Gopal, Pitchaipillai Sankar Ganesh, and Naji Naseef Pathoor
Wiley
AbstractThis comprehensive review explores the intricate relationship between gut microbiota, diet, and insulin resistance, emphasizing the novel roles of diet‐induced microbial changes in influencing metabolic health. It highlights how diet significantly influences gut microbiota composition, with different dietary patterns fostering diverse microbial communities. These diet‐induced changes in the microbiome impact human metabolism by affecting inflammation, energy balance, and insulin sensitivity, particularly through microbial metabolites like short‐chain fatty acids (SCFAs). Focusing the key mediators like endotoxemia and systemic inflammation, and introduces personalized microbiome‐based therapeutic strategies, it also investigates the effects of dietary components—fiber, polyphenols, and lipids—on microbiota and insulin sensitivity, along with the roles of protein intake and amino acid metabolism. The study compares the effects of Western and Mediterranean diets on the microbiota‐insulin resistance axis. Therapeutic implications, including probiotics, fecal microbiota transplantation (FMT), and personalized diets, are discussed. Key findings reveal that high‐fat diets, especially those rich in saturated fats, contribute to dysbiosis and increased intestinal permeability, while high‐fiber diets promote beneficial bacteria and SCFAs. The review underscores the future potential of food and microbiota interventions for preventing or managing insulin resistance.


Letter to the editor on National trends and disparities in herpes zoster vaccination among US older adults with chronic obstructive pulmonary disease (COPD), 2008 to 2022
Rajesh Kanna Gopal, Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, and Akshaya Viswanathan
Elsevier BV



Letter to the editor regarding, “Impact of post-operative transoral robotic surgery hemorrhage on adjuvant treatment delays in patients with oropharyngeal squamous cell carcinoma”
Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, and Rajesh Kanna Gopal
Elsevier BV



Letter to the editor regarding “Surgical management of naso-orbito-ethmoidal fractures: a systematic review”
Naji Naseef Pathoor, Rajesh Kanna Gopal, and Pitchaipillai Sankar Ganesh
Elsevier BV



Response from the authors Vilas-Franquesa et al.
Naji Naseef Pathoor, Pitchaipillai Sankar Ganesh, and Rajesh Kanna Gopal
Elsevier BV



Letter to the Editor: Refer to the review article on the food by-products bioprocess wheel: A guidance tool for the food industry by Vilas-Franquesa et al., (2024)
Naji Naseef Pathoor, Pitchaipillai Sankar Ganesh, and Rajesh Kanna Gopal
Elsevier BV



Letter to the Editor on an Original Research Article, Post-irradiation Dysbiosis in Patients With Nasopharyngeal Carcinoma Having Received Radiotherapy–A Pilot Study
R.K. Gopal, P. Sankar Ganesh, and N.N. Pathoor
Elsevier BV



Letter to the editor regarding “Induction chemotherapy regimes in first-line treatment for locoregionally advanced nasopharyngeal carcinoma: A network meta-analysis and cost-effectiveness analysis
Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor, and Rajesh Kanna Gopal
Elsevier BV



Letter to the editor regarding, “Exploring diagnostic frontiers in oral squamous cell carcinoma: A comprehensive review from immunohistochemistry to genomic profiling”
Naji Naseef Pathoor, Pitchaipillai Sankar Ganesh, and Rajesh Kanna Gopal
Elsevier BV



Letter to the editor on “A review: Exploring the role of ChatGPT in the diagnosis and treatment of oral pathologies”
Naji Naseef Pathoor, Gopal Rajesh Kanna, and Pitchaipillai Sankar Ganesh
Elsevier BV



Extraction, characterization and the antioxidant activity of carotenoid pigment canthaxanthin from an aero-terrestrial and filamentous green microalga Trentepohlia sp.
Elumalai Sanniyasi, Rajesh Kanna Gopal, Preethy P. Raj, Kalaiselvi R., and Chandhinipriya S.
Elsevier BV



Bioaccumulation of Titanium in diatom Cyclotella atomus Hust
Elumalai Sanniyasi, Rajesh Kanna Gopal, Rajesh Damodharan, Tarani Thirumurugan, and Vishali Mahendran
Springer Science and Business Media LLC



Biofilm in Aquaculture Microorganisms
Naseef Pathoor Naji, Natarajan Chandrakala, Jayaraman Eswari, Sellamuthu Shanmugapriya, R.V. Geetha, Rajesh Kanna Gopal, Saravanan Shanmugam, Gulshan Wadhwa, and Pitchaipillai Sankar Ganesh
CRC Press

RECENT SCHOLAR PUBLICATIONS

Letter to the Editor Regarding the Article “PTV Margins in MR-guided and Beam-gated SBRT of Liver Metastases: GTV Dose Escalation Can Reduce the Required PTV”
A Viswanathan, PS Ganesh, RK Gopal
Clinical Oncology 40 2025



Reflection on Transoral Robotic Surgery vs Transoral Laser Microsurgery in HPV-Positive Oropharyngeal Squamous Cell Carcinoma—Reply
JT O’Hara, CN Hurt, TM Jones
JAMA Otolaryngology–Head & Neck Surgery 2025



Letter to the Editor regarding the article “Learning curve for robot-assisted Mckeown esophagectomy in patients with thoracic esophageal cancer”
PS Ganesh, RK Gopal
European Journal of Surgical Oncology 2025



A rapid, reliable, and revolutionary dual-path platform assay: a paradigm in typhoid diagnosis
RK Gopal, PS Ganesh, NN Pathoor, A Viswanathan
The Lancet Microbe 2025



Mpox vaccination strategies in DR Congo
RK Gopal, PS Ganesh, NN Pathoor
The Lancet Global Health 13 (3), e415 2025



Letter to the Editor Regarding the Article “Effective Strategies for the Prevention and Mitigation of Phosphatidylinositol-3-Kinase Inhibitor-Associated Hyperglycemia
RK Gopal, PS Ganesh
Clinical Breast Cancer 2025



Letter to the editor regarding “Applications of artificial intelligence for surgical extraction in atomatology: a systematic review”
PS Ganesh, NN Pathoor, GR Kanna
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139 (1), 124 2025



Letter to the editor regarding" Influenza vaccination and COVID-19 infection risk and disease severity: A systematic review and multilevel meta-analysis of prospective studies"
PS Ganesh, NN Pathoor, RK Gopal, A Viswanathan, EM Shankar
American journal of infection control 53 (1), 167 2025



Letter to the Editor Regarding the Article “The Impact of COVID-19 on Breast Cancer Care: A Qualitative Analysis of Surgeons’ Perspectives”
PS Ganesh, NN Pathoor, RK Gopal
Clinical Breast Cancer 25 (1), e100-e102 2025



Correspondence to the Editor: Performance of Multimodal Artificial Intelligence Chatbots Evaluated on Clinical Oncology Cases
RK Gopal, PS Ganesh, NN Pathoor
Clinical oncology (Royal College of Radiologists (Great Britain)) 37, 103684 2025



Functional antibody responses associated with effectiveness of RTS, S malaria vaccine in children: new insights and implications
RK Gopal, PS Ganesh, NN Pathoor
The Lancet Microbe 6 (1) 2025



3-Hydroxybenzoic acid inhibits the virulence attributes and disrupts biofilm production in clinical isolates of Acinetobacterbaumannii
NN Pathoor, PS Ganesh, AR Anshad, RK Gopal, EM Ponmalar, ...
European Journal of Clinical Microbiology & Infectious Diseases, 1-17 2024



Microbiome interactions: Acinetobacter baumannii biofilms as a co-factor in oral cancer progression
NN Pathoor, PS Ganesh, RK Gopal
World Journal of Microbiology and Biotechnology 40 (12), 398 2024



Synergistic interplay of diet, gut microbiota, and insulin resistance: Unraveling the molecular nexus
RK Gopal, PS Ganesh, NN Pathoor
Molecular Nutrition & Food Research 68 (23), 2400677 2024



Letter to the editor on National trends and disparities in herpes zoster vaccination among US older adults with chronic obstructive pulmonary disease (COPD), 2008 to 2022
RK Gopal, PS Ganesh, NN Pathoor, A Viswanathan
American journal of infection control 52 (12), 1477-1478 2024



Letter to the editor regarding,“Impact of post-operative transoral robotic surgery hemorrhage on adjuvant treatment delays in patients with oropharyngeal squamous cell carcinoma”
PS Ganesh, NN Pathoor, RK Gopal
Oral Oncology 159, 107091 2024



Letter to the Editor regarding the article" Effectiveness and Safety of Pyrotinib-Based Therapy in the Treatment of HER2-Positive Breast Cancer Patients with Brain Metastases
A Viswanathan, NN Pathoor, RK Gopal, PS Ganesh
Clinical breast cancer 24 (8), e773-e774 2024



Letter to the Editor regarding," An up to thirty-year retrospective study on the success and survival of single unit and splinted implant-supported crowns in a dental school
PS Ganesh, NN Pathoor, RK Gopal
The Journal of prosthetic dentistry, S0022-3913 (24) 00746-7 2024



Enhancing microbiome-based biomarkers: challenges and opportunities
RK Gopal, PS Ganesh, NN Pathoor, A Viswanathan
The Lancet Microbe 2024



Letter to the Editor on an Original Research Article, Post-irradiation Dysbiosis in Patients With Nasopharyngeal Carcinoma Having Received Radiotherapy–A Pilot Study
RK Gopal, PS Ganesh, NN Pathoor
Clinical Oncology 36 (11), e470-e471 2024

MOST CITED SCHOLAR PUBLICATIONS

Biodegradation of polyethylene by green photosynthetic microalgae
RV Kumar, GR Kanna, S Elumalai
J Bioremediat Biodegrad 8 (381), 2 2017
Citations: 195



Biodegradation of low-density polyethylene (LDPE) sheet by microalga, Uronema africanum Borge
E Sanniyasi, RK Gopal, DK Gunasekar, PP Raj
Scientific Reports 11 (1), 17233 2021
Citations: 100



In vitro anti-HIV-1 activity of the bioactive compound extracted and purified from two different marine macroalgae (seaweeds)(Dictyota bartayesiana JV Lamouroux and Turbinaria
E Sanniyasi, G Venkatasubramanian, MM Anbalagan, PP Raj, RK Gopal
Scientific reports 9 (1), 12185 2019
Citations: 54



Retrospective and prospective application of robots and artificial intelligence in global pandemic and epidemic diseases
A Yoganandhan, GR Kanna, SD Subhash, JH Jothi
Vacunas (English Edition) 22 (2), 98-105 2021
Citations: 28



In vitro anticancer potential of laminarin and fucoidan from Brown seaweeds
E Sanniyasi, RK Gopal, R Damodharan, A Arumugam, M Sampath Kumar, ...
Scientific Reports 13 (1), 14452 2023
Citations: 26



Industrial production of Superoxide Dismutase (SOD): a mini review
RK Gopal, S Elumalai
J. Probiot. Health 5 (179), 10.4172 2017
Citations: 18



Extraction of carotenoid and thin layer chromatography (TLC), GC-MS, FT-IR and HPLC analysis of pharmaceutically important pigment astaxanthin from a new strain of
S Elumalai, BI Santhose, GR Kanna
Weekly Science Research Journal 2 (8), 2321-7871 2014
Citations: 18



Characterization and in vitro anticancer potential of exopolysaccharide extracted from a freshwater diatom Nitzschia palea (Ktz.) W.Sm. 1856
RKGRD Elumalai Sanniyasi, Antony Prakash Rejoy Patrick, Kreedika Rajagopalan
Scientific Reports 12, 22114 2022
Citations: 13



Anti-inflammatory, remorin-like protein from green marine Macroalga Caulerpa sertularioides (SG Gmel.) M. Howe
E Sanniyasi, RK Gopal, PP Raj, AK Shanmugavel
Heliyon 9 (8) 2023
Citations: 9



Biodegradation of low-density polyethylene (LDPE) sheet by microalga, Uronema Africanum Borge. Sci Rep 11: 17233
E Sanniyasi, RK Gopal, DK Gunasekar, PP Raj
2021
Citations: 7



Synthesis of bioethanol by dark fermentation using marine seaweed Acanthophora spicifera (Vahl.) borgesen as a cheap substrate
A Umamaheswari, P Saranraj, G Rajesh Kanna, S Elumalai, T Sangeetha
Bioenergetics 6 (146), 2 2017
Citations: 7



Extraction of phycocyanin an important pharmaceutical phycobiliproteins from cyanobacteria
S Elumalai, KG Rajesh, G Jegan, T Sangeetha, SD Roop
Int J Pharm Res Dev 6 (4), 67-74 2014
Citations: 7



Airlift photobioreactor cultivation of a new strain of Haematococcus pluvialis collected from high altitude regions of Himalayas
B Infant Santhose, S Elumalai, G Rajesh Kanna
International Journal of Science and Research 3 (10), 2289-2292 2014
Citations: 6



Biodegradation of polyethylene by green photosynthetic microalgae. J Bioremed Biodegrad 8: 1–9
RV Kumar, GR Kanna, S Elumalai
2017
Citations: 5



Biodegradation of Polyethylene by Green Photosynthetic Microalgae. J. bioremediat. biodegrad., 08 (01)
R Vimal Kumar, GR Kanna, S Elumalai
2017
Citations: 5



Investigating the anti-inflammatory and anti-arthritis effects of fucoidan from a brown seaweed
PP Raj, RK Gopal, E Sanniyasi
Current Research in Biotechnology 7, 100220 2024
Citations: 4



Biodegradation of low-density polyethylene (LDPE) sheet by microalga. Uronema africanum Borge Sci Rep 11 (1): 17233
E Sanniyasi, RK Gopal, DK Gunasekar, PP Raj
2021
Citations: 4



Synergistic interplay of diet, gut microbiota, and insulin resistance: Unraveling the molecular nexus
RK Gopal, PS Ganesh, NN Pathoor
Molecular Nutrition & Food Research 68 (23), 2400677 2024
Citations: 3



Production and Evaluation of a Seaweed-Based Bioplastic Sheet for Food Packaging
RVRKG Janani, Sathiamurthy, Geetha
Uttar Pradesh Journal of Zoology 45 (14), 108-115 2024
Citations: 3



Bioaccumulation of Titanium in diatom Cyclotella atomus Hust
E Sanniyasi, RK Gopal, R Damodharan, T Thirumurugan, V Mahendran
Biometals 37 (1), 71-86 2024
Citations: 3

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

1. Title of the Invention: Brewing of Alcoholic Beverage (Beer) from a Marine Seaweed.
Patent Application Number: 202241036660, Status: Applied
2. Title of the Invention: Blue-green tea: the future of beverages.
Status: Filing under process