Luis Alberto Gobbo
@fct.unesp.br
Associate Professor, Kinesiology Department, School of Technology and Science
São Paulo State University - UNESP
Post-doctor in Exercise Science and a PhD in Public Health, Professor Gobbo has a PhD internship (PDEE / CAPES) at the School of Human Motricity of the Technical University of Lisbon and is a Visiting Scholar at Harvard Medical School. He is currently an Associate Professor in the Department of Physical Education/Kinesiology at the School of Technology and Science (FCT) at Sao Paulo State University-UNESP, Presidente Prudente / SP, Brazil, and accredited in the Graduate Program in Movement Sciences at UNESP. He coordinates the Musculoskeletal System Assessment Laboratory (LABSIM), in partnerships with Brazilian, American, Italian and Portuguese institutions, and has supervised more than 20 master's and doctoral students, in addition to two postdoctoral supervisions. He has two book chapters published and more than 80 articles published in indexed journals.
EDUCATION
Mar 2024 – Aug 2024 Harvard Medical School
Visiting Scholar, Laboratory of Exercise Physiology and Physical Performance, Men's Health, Aging, and Metabolism Unit, Harvard Medical School, Harvard University, Boston, MA, USA
Feb 2017 – Jan 2018 Londrina State University - UEL
Post-Doctoral, Exercise Science
Londrina, Paraná, Brazil
Feb 2008 – Mar 2012 University of São Paulo – USP
Doctor of Philosophy, Nutrition in Public Health
São Paulo, São Paulo, Brazil
Feb 2006 – Sep 2007 Londrina State University - UEL
Master of Science, Physical Education
Londrina, Paraná, Brazil
Feb 2000 – Apr 2004 Londrina State University - UEL
Bachelor of Science, Physical Education
Londrina, Paraná, Brazil
RESEARCH, TEACHING, or OTHER INTERESTS
Aging, Public Health, Environmental and Occupational Health, Physiology, Statistics and Probability
FUTURE PROJECTS
BIA Brasil: a national multicenter collaboration project
The project "BIA Brasil: A National Multicenter Collaboration Study" aims to establish normative values and tolerance ellipses for bioelectrical impedance parameters, including phase angle (AngF) and bioelectrical impedance vector analysis (BIVA), in a comprehensive sample of Brazilian university staff and their immediate family members. Through a cross-sectional design, which will later serve as a basis for longitudinal studies, data will be collected at 25 research centers distributed across the five regions of Brazil. Body composition parameters will be assessed using bioelectrical impedance spectroscopy (BIS) and localized assessment methods (L-BIA), in addition to evaluating sociodemographic variables, lifestyle habits, mental health, physical activity, sedentary behavior, and quality of life.
Applications Invited
Partnerships, grants
Analysis of bioelectrical impedance parameters and association with health determinants in families with high and low social vulnerability: BIA Brasil project
The project aims to investigate bioelectrical impedance (BIA) parameters and their association with health determinants in families with different levels of social vulnerability. This study will compare two groups: university employees in Presidente Prudente, SP, and their direct relatives (low social vulnerability) and residents from a peripheral neighborhood in Álvares Machado, SP (high social vulnerability), matched by age and sex. In addition to BIA parameters, evaluations will include body composition, quality of life, nutritional habits, physical activity levels, and clinical outcomes. The analysis will seek to identify patterns associated with social vulnerability and provide support for public health interventions that promote equity and well-being.
Applications Invited
Partnerships, grants
Analysis of different volumes and intensities of training on bioelectrical impedance parameters in young university students and athletes
The present study compares the BIA and L-BIA parameters in physical training sessions with varying volumes and intensities in young adults with experience in physical activities. To this end, physically active young people of both sexes, aged between 18 and 40, will be recruited to perform RT sessions in different zones of training volume and intensities. The BIA and L-BIA parameters will be measured using electrical bioimpedance, using a 50 kHz frequency analyzer. Resistance and reactance measurements will be obtained to calculate the phase angle. L-BIA will be performed on muscles specific to the sports training modality. Acute assessments will be carried out pre-training, immediately post-training, and then at minutes 15', 30', 45' and 60' post-training, and 24 hours after the training session. Chronic assessments will be carried out in periods of 4 weeks after the start of training.
Applications Invited
Partnerships, grants
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Gianfranco Sganzerla, Luis Alberto Gobbo, André Luiz Bisel Mendonça, Fabricio Cesar de Paula Ravagnani, Silvio Assis de Oliveira-Junior, Vitor Cordeiro, and Christianne F. Coelho-Ravagnani
Elsevier BV
Karina Pozo, Luis Alberto Gobbo, Rafael Mello Fontolan Vieira, Amanda Mendes Cavalcante, Isis Grigoletto, and Ercy Mara Cipulo Ramos
Ovid Technologies (Wolters Kluwer Health)
Bruna T. C. Saraiva, Emerson Franchini, Alex S. Ribeiro, Luís A. Gobbo, Marília A. Correia, Luiz C. M. Vanderlei, Gerson Ferrari, William R. Tebar, and Diego G. D. Christofaro
Springer Science and Business Media LLC
Marcos Raphael Pereira-Monteiro, José Carlos Aragão-Santos, Alan Bruno Silva Vasconcelos, Antônio Gomes de Resende-Neto, André Filipe Santos de Almeida, Luis Alberto Gobbo, Francisco Hermosilla-Perona, Juan Ramón Heredia-Elvar, Fabricio Boscolo Del Vecchio, Felipe J. Aidar,et al.
MDPI AG
Encouraging healthy aging in postmenopausal women involves advocating for lifestyle modifications, including regular physical exercise like combined training (CT) and functional training (FT). Regarding this population, age-related alterations in body composition, such as decreased muscle mass and heightened adipose tissue, impact health. The aim of this study was to analyze the effects of FT and CT on body recomposition in postmenopausal women. About the methods, we randomly allocated 96 post-menopausal women to the FT, CT, or control group (CG). We measured body composition by bioimpedance and lower limb muscle strength by sit-to-stand test in five repetitions, respectively. The training protocol lasted 16 weeks, and we measured body composition and lower limb muscle strength every 4 weeks, totaling five assessments. Regarding results, we notice that both training groups increased lean mass from the 8th week of training. In addition, a reduction was observed in total fat percentage and an increase in appendicular lean mass from the 12th week of intervention. No differences were found for body mass. Furthermore, only the experimental groups increase muscle strength, starting from the 4th week of training. The conclusion was that FT and CT promote similar adaptations in body recomposition without affecting body mass in postmenopausal women.
Ricardo R. Agostinete, André O. Werneck, Pedro H. Narciso, Esther Ubago-Guisado, Manuel J. Coelho-e-Silva, Renata M. Bielemann, Luis Alberto Gobbo, Bruna Turi Lynch, Romulo Araújo Fernandes, and Dimitris Vlachopoulos
Springer Science and Business Media LLC
Abstract Background Sports practice during adolescence is important to enhance bone development, although it may provide different effects depending on the mechanical impact present in the sport. Besides, resistance training (RT) may also induce bone changes directly (via muscle contractions) and indirectly (via myokines). However, there have been no studies analyzing the longitudinal influence of engaging in sport with and without added mechanical load. Thus, this study aims to analyze the combined effects of sports participation and resistance training on areal bone mineral density (aBMD) accrual in adolescent athletes participating in swimming and impact sports for 12-months. Methods This was a 12-month longitudinal study. The sample comprised 91 adolescents (21 females) aged 10 to 18 years, engaged in impact sports (basketball, tennis, track & field, baseball and gymnastics, n = 66) and non-impact sport (swimming, n = 25). The sample was divided according to resistance training participation: impact sports only (n = 45), impact sports + resistance training (n = 21), swimming-only (n = 17) and swimming + resistance training (n = 8). aBMD and soft tissues were measured using dual-energy X-ray absorptiometry. Generalized linear models analysis was used for the resistance training (RT) x type of sport interaction in predicting aBMD changes overtime, adjusting for maturation, sex and baseline aBMD. Results After 12-months, all groups showed a significant increase in aBMD, except for the swimming groups (regardless of resistant training), which showed a significant loss in spine aBMD (-0.045 [-0.085 to -0.004] g/cm2 in swimming-only and − 0.047 [-0.073 to -0.021] g/cm2 in swimming + RT). In comparisons between groups, only swimming + RT group, compared with swimming-only group presented higher upper limbs aBMD (0.096 g/cm2 [0.074 to 0.118] in swimming + RT vs. 0.046 [0.032 to 0.060] g/cm2 in swimming only; p < 0.05) and whole body less head (WBLH) aBMD (0.039 [0.024 to 0.054] g/cm2 in swimming + RT vs. 0.017 [0.007 to 0.027] g/cm2 swimming-only; p < 0.05). Conclusion Despite the significant gain in aBMD in all groups and body sites after 12-months, except for the spine site of swimmers, the results indicate that participation in RT seems to improve aBMD accrual in swimmers at the upper limbs and WBLH.
Giovanni Henrique Quizzini, Caroline Galan de Souza Pereira, Vanessa Ribeiro dos Santos, Vitor Cabrera Batista, Bruna Spolador de Alencar Silva, Fábio Santos Lira, Alex Silva Ribeiro, and Luís Alberto Gobbo
Wiley
AbstractThe objective of the present study is to analyze the changes in bioimpedance vector analysis (BIVA) and phase angle (PhA) in sarcopenic older people submitted to a 12‐week resistance training (RT) program according to classic and specific analyses. To this end, 20 sarcopenic older adults of both sexes, invited through media, underwent bioimpedance analysis before and after the RT carried out three times a week, for 12 weeks. The mean impedance vectors of the groups established for the confidence ellipses (95% of the confidence ellipse) are compared using Hotelling's T2 test. The distance D from Mahalanobis is also calculated. Classic and Specific BIVA are presented. The resistance values for the classical analyses (R/H) decreased across all groups (whole group, women and men, p < 0.05), with approximate decreases ranging from 9.4% to 10%, while the classic reactance (Xc/H) decreased (p < 0.05) only for the whole group (5.9%) and men (7.7%). For the specific BIVA, trends are verified for the whole sample, with a decrease in resistance (R.sp) and an increase in reactance (Xc.sp). In conclusion, the RT program in sarcopenic individuals promoted a reduction in resistance values in classical analyses, indicating a possible increase in hydration status and, consequently, musculoskeletal mass.
Rafael Orbolato, Rômulo Araújo Fernandes, Bruna Camilo Turi-Lynch, Monique Yndawe Castanho Araujo, Izabela dos Santos Ferro, Luis Alberto Gobbo, Everton Alex Carvalho Zanuto, and Jamile Sanches Codogno
FapUNIFESP (SciELO)
Abstract: Leisure-time physical activity seems relevant to prevent the development of chronic diseases and obesity. However, not much is known about the economic burden of these healthy behaviors, mainly in longitudinal designs. This study aimed to analyze the impact of walking and cycling on leisure-time on adiposity and healthcare costs among adults. This longitudinal study was conducted at a medium-size Brazilian city and included 198 participants with no missing data attended in the Brazilian Unified National Health System. Cycling and walking were assessed by a questionnaire with a face-to-face interview at four time-points (baseline, 6-month, 12-month, and 18-month). Healthcare costs were assessed using medical records. Adiposity markers included waist circumference and body fatness. Over the follow-up period, participants who were more engaged in cycling presented lower body fatness (p-value = 0.028) and healthcare costs (p-value = 0.038). However, in the multivariate model, the impact of cycling on costs was not significant (p-value = 0.507) due to the impact of number of chronic diseases (p-value = 0.001). Cycling on leisure-time is inversely related to adiposity in adults, whereas its role on preventing chronic diseases seems the main pathway linking it to cost mitigation.
Analiza M. Silva, Francesco Campa, Silvia Stagi, Luís A. Gobbo, Roberto Buffa, Stefania Toselli, Diego Augusto Santos Silva, Ezequiel M. Gonçalves, Raquel D. Langer, Gil Guerra-Júnior,et al.
Springer Science and Business Media LLC
Vanessa Ribeiro Dos Santos, Bruna Spolador de Alencar Silva, Ricardo Ribeiro Agostinete, Vitor Cabrera Batista, and Luís Alberto Gobbo
Springer Science and Business Media LLC
Pedro Gabriel Pito, Ezequiel Moreira Gonçalves, Vitor Hugo Fernando de Oliveira, Rafael Deminice, Luis Alberto Gobbo, and Débora Alves Guariglia
Elsevier BV
Francesco Campa, Lucas Antonio Colognesi, Tatiana Moro, Antonio Paoli, Andrea Casolo, Leandro Santos, Rafael Ribeiro Correia, Ítalo Ribeiro Lemes, Vinícius Flávio Milanez, Diego Destro Christofaro,et al.
Springer Science and Business Media LLC
AbstractResistance training has been proposed as a valid practice to counteract the aging effect on body mass and its components, which can be easily evaluated though the bioelectrical impedance analysis. This study aimed to achieve a systematic review with meta-analysis on the impact of resistance training on bioelectrical proprieties in older adults.A literature review was done in four electronic databases up to 1 January 2022. The inclusion criteria were: (i) participants aged ≥ 60 years; (ii) resistance training lasted ≥ 8 weeks; (iii) measurement of raw bioelectrical parameters in randomized controlled study designs.The outcomes of the trial had to be bioelectrical phase angle (PhA), resistance (R), and reactance (Xc). The methodological quality was assessed using the Rosendal scale.Overall, seven studies with a total of 344 participants were eligible for the analysis. The quality assessment yielded a score of 71.3%. Bioelectrical PhA (0.52 degree [95%CI 0.32, 0.71], p < 0.001) and Xc (3.58 ohms [95%CI 1.97, 5.19], p < 0.001) increased, whereas R decreased (-28.50 ohms [95%CI -41.39, -15.60], p < 0.001) after the resistance training programs.In this meta-analysis, resistance training promoted increases of PhA, which result from an increase in Xc concomitant with a reduction in R. According to the bioimpedance vector analysis, resistance-trained people experienced a beneficial leftward vector displacement, whilst inactivity induced a rightward vector displacement within the R-Xc graph. In future, more sophisticated and rigorous studies that address specific criteria, methods and targeted designs are required to identify which equipment and protocols allow for an optimization of the resistance training effects.Registration code in PROSPERO: CRD42020168057.
Jefferson M. de Souza, William R. Tebar, Leandro D. Delfino, Fernanda S.G. Tebar, Luis A. Gobbo, Marcia Franco, Claudiele C.M. da Silva, Crystian B.S. Oliveira, and Diego G.D. Christofaro
Elsevier BV
Marcos Raphael Pereira Monteiro, Alan Pantoja Cardoso, Antônio Gomes de Resende-Neto, Alan Bruno Silva Vasconcelos, Enilton Aparecido Camargo, Luis Alberto Gobbo, José Luis Maté-Muñoz, Juan Ramón Heredia-Elvar, David George Behm, and Marzo Edir Da Silva-Grigoletto
Frontiers Media SA
Introduction: Increases in fat mass and reductions in lean mass are associated with the frailty and mortality of older people. In this context, Functional Training (FT) is an option to increase lean mass and reduce fat mass in older people. Thus, this systematic review aims to investigate the effects of FT on body fat and lean mass in older people.Methods: We included randomized controlled clinical trials, with at least one intervention group that employed FT, with the age of participants ≥60 years; and participants physically independent and healthy. We performed the systematic investigation in Pubmed MEDLINE, Scopus, Web of Science, Cochrane Library, and Google Scholar. We extracted the information and used the PEDro Scale to assess the methodological quality of each study.Results: Our research found 3,056 references with five appropriate studies. Of the five studies, three presented reductions in fat mass, all of them with interventions between three and 6 months, different training dose parameters, and 100% of the sample was composed of women. On the other hand, two studies with interventions between 10 and 12 weeks presented conflicting results.Conclusion: Despite the limited literature about lean mass, it appears that long-term FT interventions may reduce fat mass in older women.Clinical Trial Registration:https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=399257, identifier CRD42023399257
Isis Grigoletto, Vinicius Cavalheri, Luis Alberto Gobbo, Karina Pozo, Enio Rodrigues Maia Filho, Diogo Gonçalves Ribeiro, Nara Ielo, Fabiano Francisco De Lima, and Ercy Mara Cipulo Ramos
JMIR Publications Inc.
Background Lung or head and neck cancers are known for their high prevalence and mortality rates. Chemotherapy and radiotherapy are usually recommended as cancer treatment for these malignancies; however, they can negatively impact both the physical and mental status of patients. Hence, it is reasonable to consider resistance and aerobic exercise training to prevent these negative health outcomes. Further, several factors prevent patients from attending outpatient exercise training programs, and, therefore, a semisupervised home-based exercise training program may be seen as a well-accepted alternative. Objective The aim of this study will be to investigate the effects of a semisupervised home-based exercise training program on physical performance, body composition, and self-reported outcomes; changes in the initial cancer treatment dose prescribed; number of hospitalizations at 3, 6, and 9 months; and 12-month survival in people with primary lung or head and neck cancer. Methods Participants will be randomly allocated to the training group (TG) or control group (CG). The TG will undergo semisupervised home-based resistance and aerobic exercise training throughout their cancer treatment. The resistance training will be performed using elastic bands (TheraBand) twice a week. The aerobic training (ie, brisk walk) will be performed for at least 20 minutes per day outdoors. The equipment and tools used during the training sessions will be provided. This intervention will start the week before treatment commencement, will be performed throughout the duration of the treatment, and will continue for 2 weeks after treatment completion. The CG will undergo usual care (ie, cancer treatment with no formal exercise prescription). Assessments will take place 2 weeks before the beginning of the usual cancer treatment and 2 weeks after treatment completion. The measures of physical function (peripheral muscle strength, functional exercise capacity, and physical activity), body composition, and self-reported outcomes (symptoms of anxiety and depression, health-related quality of life, and symptoms related to the disease and treatment) will be collected. We will report on any change in the initial cancer treatment dose prescribed; number of hospitalizations at 3, 6, and 9 months; and 12-month survival. Results In February 2021, the clinical trial registration was approved. Recruitment and data collection for the trial are ongoing (as of April 2023, 20 participants had already been randomized), and findings of this study are likely to be published late in 2024. Conclusions This exercise training as a complementary treatment for patients with cancer is likely to promote positive effects on the health outcomes assessed, over and above any change in the CG, and prevent the reduction of initial cancer treatment dose prescribed. If these positive effects are shown, they will likely impact long-term outcomes such as hospitalizations and 12-month survival. Trial Registration Brazilian Clinical Trials Registry (ReBEC) RBR-5cyvzh9; https://ensaiosclinicos.gov.br/rg/RBR-5cyvzh9. International Registered Report Identifier (IRRID) PRR1-10.2196/43547
Josefina Bertoli, Ewertton de Souza Bezerra, Kerri M. Winters-Stone, Luis Alberto Gobbo, and Ismael Forte Freitas
Informa UK Limited
Abstract Purpose To evaluate the effects of 24 weeks of Mat Pilates in breast cancer survivors (BCS) undergoing hormone therapy on lower and upper body muscle strength parameters and flexibility. Materials and methods Forty-three BCS (≥40 years) with confirmed breast cancer stage 0–III undergoing hormone therapy were included. Participants were randomized into Mat Pilates (three times/week, 60 min session) or control group (relaxation activities every two weeks). The difficulty and number of exercise repetitions were increased over the weeks. Assessments were performed at three times points (baseline, 12 weeks, and 24 weeks). The generalized estimating equations (GEE) model was used to compare each outcome measure during the analysis of intention to treat (ITT) and “Per protocol analysis” (PPA). Results The Pilates group presented significantly increased (p < 0.05) isometric flexor–extensor PT, and concentric and eccentric flexor PT and mechanical work (MW) after the intervention. Most of the upper body strength parameters, time to achieve maximal force (TFmax), maximal force (F max), and rapid force index (RFI) and right-left upper and lower body flexibility (p < 0.05) also improved. Conclusions From our findings, we conclude that 24 and 12-weeks of Mat Pilates induced strength and flexibility gains for lower and upper body, respectively. Implications for rehabilitation Mat Pilates can be adapted to the fitness level of breast cancer survivors, with a great variety of exercises that can be performed using a mat only or a few pieces of equipment. Patients can practice at home to gain different health benefits (i.e., increasing strength, flexibility, and functional capacity level), which could positively impact on quality of life. Mat Pilates performed three times per week with systematized increments in exercise level, load, and volume throughout the intervention was effective to improve hip extensor–flexor muscles peak torque and mechanical work at different muscle contractions, as well as upper and lower body flexibility. Mat Pilates was also able to improve right-left shoulder abductor and trunk extensor muscles strength parameters after 12 weeks of intervention, as well as both surgery and non-surgery sides of the upper body.
Catarina Covolo Scarabottolo, William Rodrigues Tebar, Luis Alberto Gobbo, David Ohara, Aline Duarte Ferreira, Daniel da Silva Canhin, and Diego Giulliano Destro Christofaro
Health and Quality of Life Outcomes Springer Science and Business Media LLC
Abstract Background It is estimated that, worldwide, 9% of deaths occur as a result of insufficient physical activity (PA) practice. Practicing PA can prevent and/or reduce the deleterious effects of different types of diseases and can improve general health aspects related to health-related quality of life (HRQoL). Purpose To analyze the relationship of different PA domains with different HRQoL domains over a two-year period. Methods This is an observational study with a two-year longitudinal design. The sample, composed of adults, was selected from a randomization of the streets of the different regions (north, south, east, west and center) covering individuals from all areas of the city. To assess the practice of PA, the Baecke questionnaire was used. The instrument Medical Outcomes Study SF-36-Item Short Form Health Survey was used to assess the HRQoL domains. Linear regression models were used to analyzed the association of different PA domains with changes in HRQoL. Multivariate statistical models were adjusted for gender, age, socioeconomic status, marital status, the respective PA score at baseline, smoking, body mass index, and morbidity. Results 331 adults were evaluated. There was a decrease in the practice of PA in the occupational domain and an increase in the leisure/locomotion domain. Regarding HRQoL, there was an increase in the scores of body pain and mental health, and a decrease in scores of general health, vitality, social aspects and emotional aspects. The PA practice in the occupational domain was inversely related to functional capacity (β = − 7.2 [CI 95% − 13.0; − 1.4]). The practice of PA through sports in leisure time was positively associated with vitality (β = 5.5 [CI 95% 0.2; 10.7]) and mental health (β = 15.2 [CI 95% 6.8; 23.7]). PA practice during leisure and locomotion was inversely associated with functional capacity (β = − 5.68 [CI 95% − 10.7; − 0.6]) and positively associated with vitality β = 4.8 [CI 95% 0.8; 8.7]) and mental health (β = 8.4 [CI 95% 2.0; 14.9]). The total PA practice was inversely associated with functional capacity (β = − 3.8 [CI 95% − 6.5; − 1.2]) and positively associated with pain in the body (β = 4.9 [CI 95% 0.3; 9.4]), vitality (β = 2.9 [CI 95% 0.7; 5.0]) and mental health (β = 5.7 [CI 95% 2.2; 9.2]). Conclusions It is suggested that practicing PA continuously within a period of two years can positively affect some physical aspects and some mental aspects related to HRQoL, but not all of them. A strategy for public policy actions is to explore these variables by domain and thus detect the real needs and improvements that can be made for the population.
Jefferson M. de Souza, William R. Tebar, Leandro D. Delfino, Fernanda S.G. Tebar, Luis A. Gobbo, Rafael Z. Pinto, Claudiele C.M. da Silva, Crystian B.S. Oliveira, and Diego G.D. Christofaro
Elsevier BV
Witalo Kassiano, Bruna Costa, João Pedro Nunes, Letícia T. Cyrino, Matheus A. Nascimento, Crisieli Tomeleri, Melissa Antunes, Luís A. Gobbo, Alex S. Ribeiro, Manuel J. Coelho-e-Silva,et al.
Elsevier BV
Josefina Bertoli, Ewertton de Souza Bezerra, Andréa Dias Reis, Êmili Amice da Costa Barros, Luis Alberto Gobbo, and Ismael Forte Freitas Júnior
Ovid Technologies (Wolters Kluwer Health)
Abstract Bertoli, J, de Souza Bezerra, E, Dias Reis, A, Amice da Costa Barros, E, Gobbo, LA, and Forte Freitas Júnior, I. Long-term side effects of breast cancer on force production parameters. J Strength Cond Res 36(5): 1450–1458, 2022—Breast cancer treatments have long-term side effects, which are associated with muscle strength reduction, negatively affecting the quality of life and increasing the chances of a sedentary life style. The aim of this study was to analyze the effects of types of surgery and hormone therapy on muscle strength parameters in breast cancer survivors compared to women without cancer (control). Eighty-three women, 42 breast cancer survivors and 41 control women, volunteered to participate in this study. Subjects performed maximal isometric voluntary contractions, so that force parameters of the right and left shoulder abductor, trunk extensor, and preferred knee extensor-flexor muscles could be evaluated. Overall, breast cancer survivors presented a lower absolute and normalized maximal force (Fmax) for all muscle groups compared with control. The right shoulder abductor muscles of breast cancer survivors presented a significantly lower absolute and normalized rapid force index (RFI) than control. When compared according to hormone therapy treatment, in breast cancer survivors undergoing aromatase inhibitor, all strength parameters except for normalized RFI demonstrated lower values for the right and left shoulder abductors, trunk, and knee extensors compared with control and tamoxifen. When separated by surgery type, breast cancer survivors who underwent quadrantectomy and radical mastectomy presented lower values for some strength parameters for the left and right shoulder abductors, except for trunk extensor muscles, in which quadrantectomy and total mastectomy presented lower strength parameters. It is recommended that breast cancer survivors should be encouraged to perform supervised strength training programs for different muscle groups to improve Fmax and RFI, aiming to reduce muscle weakness and pain, and improve functional capacity and quality of life.
Francesco Campa, Luis Alberto Gobbo, Silvia Stagi, Leticia Trindade Cyrino, Stefania Toselli, Elisabetta Marini, and Giuseppe Coratella
Springer Science and Business Media LLC
Luis Alberto Gobbo, Raquel David Langer, Elisabetta Marini, Roberto Buffa, Juliano Henrique Borges, Mauro A. Pascoa, Vagner X. Cirolini, Gil Guerra-Júnior, and Ezequiel Moreira Gonçalves
MDPI AG
The military are selected on the basis of physical standards and are regularly involved in strong physical activities, also related to particular sports training. The aims of the study were to analyze the effect of a 7-month military training program on body composition variables and the suitability of specific ‘bioelectrical impedance vector analysis’ (spBIVA), compared to DXA, to detect the changes in body composition. A sample of 270 male Brazilian cadets (19.1 ± 1.1 years), composed of a group practicing military physical training routine only (MT = 155) and a group involved in a specific sport training (SMT = 115), were measured by body composition assessments (evaluated by means of DXA and spBIVA) at the beginning and the end of the military routine year. The effect of training on body composition was similar in SMT and MT groups, with an increase in LST. DXA and spBIVA were correlated, with specific resistance (Rsp) and reactance (Xcsp) positively related to fat mass (FM), FM%, LST, and lean soft tissue index (LSTI), and phase angle positively related to LST and LSTI. Body composition variations due to physical training were recognized by spBIVA: the increase in muscle mass was indicated by the phase angle and Xcsp increase, and the stability of FM% was consistent with the unchanged values of Rsp. Military training produced an increase in muscle mass, but no change in FM%, independently of the sample characteristics at baseline and the practice of additional sports. SpBIVA is a suitable technique for the assessment of body composition in military people.
Josefina Bertoli, Ewertton de Souza Bezerra, Sueyla Ferreira da Silva dos Santos, Luis Alberto Gobbo, and Ismael Forte Freitas Júnior
Korean Society of Exercise Rehabilitation
The aim of this study was to evaluate the influence of adherence to mat Pilates training on lower and upper body strength and flexibility in breast cancer survivors. Breast cancer survivors ( ≥ 40 years) with cancer stages 0–III undergoing hormone therapy participated in this study. For this secondary investigation only the intervention group was analyzed, divided into low and high training adherence. Participants performed a 60-min session of mat Pilates, 3 times/wk, for 24 weeks. Concentric, eccentric, and isometric hip flexor-extensor muscle peak torque, and isometric maximal strength parameters of the shoulder abductors, trunk extensors, and handgrip were assessed. Physical activity level was analyzed as a control variable. The results showed that high training adherence improved (<i>P</i>< 0.05) left shoulder abductor strength parameters and lower and upper body flexibility compared to baseline. The low training adherence group improved (<i>P</i>< 0.05) trunk extensors, right and left shoulder abductor strength parameters, handgrip strength, and extensor-flexor peak torque compared to baseline. There were no differences (<i>P</i>> 0.05) between high and low adherence for physical activity level before and after the intervention. Therefore, it appears that higher training adherence most influences some strength parameters and flexibility, while fewer sessions enable the achievement of significant results for shoulder abductor and hip extensor-flexor muscle strength parameters.
Ana Paula Coelho Figueira Freire, Carlos Augusto Marçal Camillo, Bruna Spolador de Alencar Silva, Juliana Souza Uzeloto, Fabiano Francisco de Lima, Luis Alberto Gobbo, Dionei Ramos, and Ercy Mara Cipulo Ramos
Informa UK Limited
ABSTRACT Purpose: To compare the effects of three modalities of resistance training, two using elastic components and one using conventional weight machine on peripheral muscle strength in Individuals with chronic obstructive pulmonary disease (COPD). Effects on exercise capacity, impact of disease on health status, body composition and daily level of physical activity were investigated as secondary endpoints. Methods: Forty-eight participants were randomly allocated (Trials Registry #RBR-6V9SJJ) into Elastic band group (Theraband®) (EBG), Elastic tubes training using Lemgruber® (ETG), and Conventional training with weight machine equipment (CG). Participants were evaluated before and after 12 weeks of training regarding peripheral muscle strength by dynamometry; impact of disease on health status via COPD Assessment Test, CAT; exercise capacity by 6-min walk test, 6MWT; body composition by bioelectrical impedance; and daily level of physical activities via accelerometry. Results: Inter-group comparison of training effects did not elucidate significant differences between the modalities in muscle strength (p ≥ .2). Likewise, all training modalities showed similar effects on CAT, body composition and daily physical activity variables with no statistical significance observed (p ≥ .15). Conclusions: Modalities of resistance training using elastic components presented similar effects on muscle strength, health status, exercise capacity, body composition and daily level of physical activity in individuals with COPD. The effects of elastic resistance were similar to conventional resistance training.
Fábio Santos Lira, Telmo Pereira, Luciele Guerra Minuzzi, Caique Figueiredo, Tiago Olean-Oliveira, Ana Paula Coelho Figueira Freire, Manuel João Coelho-e-Silva, Armando Caseiro, Ronaldo Vagner Thomatieli-Santos, Vanessa Ribeiro Dos Santos,et al.
International Journal of Environmental Research and Public Health MDPI AG
Background: This proposal aims to explain some of the gaps in scientific knowledge on the natural history of coronavirus disease (COVID-19), with a specific focus on immune, inflammatory, and metabolic markers, in parallel with temporal assessment of clinical and mental health in patients with COVID-19. The study will explore the temporal modulatory effects of physical activity and body composition on individual trajectories. This approach will provide a better understanding of the survival mechanisms provided by the immunomodulatory role of physical fitness. Methods: We will conduct a prospective observational cohort study including adult patients previously infected with the SARS-CoV-2 virus who have expressed a mild to moderate COVID-19 infection. Procedures will be conducted for all participants at baseline, six weeks after vaccination, and again at 12 months. At each visit, a venous blood sample will be collected for immune phenotypic characterization and biochemistry assays (inflammatory and metabolic parameters). Also, body composition, physical activity level, cardiovascular and pulmonary function, peripheral and respiratory muscle strength, functional exercise capacity, and mental health will be evaluated. Using the baseline information, participants will be grouped based on physical activity levels (sedentary versus active), body composition (normal weight versus overweight or obese), and SARS-CoV-2 status (positive versus negative). A sub-study will provide mechanistic evidence using an in-vitro assay based on well-trained individuals and age-matched sedentary controls who are negative for SARS-CoV-2 infection. Whole blood will be stimulated using recombinant human coronavirus to determine the cytokine profile. Peripheral blood mononuclear cells (PBMCs) from healthy well-trained participants will be collected and treated with homologous serum (from the main study; samples collected before and after the vaccine) and recombinant coronavirus (inactive virus). The metabolism of PBMCs will be analyzed using Respirometry (Seahorse). Data will be analyzed using multilevel repeated-measures ANOVA. Conclusions: The data generated will help us answer three main questions: (1) Does the innate immune system of physically active individuals respond better to viral infections compared with that of sedentary people? (2) which functional and metabolic mechanisms explain the differences in responses in participants with different physical fitness levels? and (3) do these mechanisms have long-term positive modulatory effects on mental and cardiovascular health? Trial registration number: Brazilian Registry of Clinical Trials: RBR-5dqvkv3. Registered on 21 September 2021.
Bruna Thamyres Ciccotti Saraiva, Ricardo Ribeiro Agostinete, Ismael Forte Freitas Júnior, Daniel Eduardo Rodrigues de Sousa, Luis Alberto Gobbo, William Rodrigues Tebar, and Diego Giulliano Destro Christofaro
Springer Science and Business Media LLC
Abstract Background To examine the association of handgrip strength (HGS) and bone mineral density (BMD) of Brazilian children and adolescents. Methods The sample included 243 children and adolescents aged from 4 to 15 years (9.3 ± 2.2 years), 171 males and 72 females. The following measurements were performed: weight, height, trunk length, and years to the peak height velocity (PHV). The percentage lean soft tissue (PLST), percentage fat mass (PFM), and BMD were obtained using Dual Energy X-ray Absorptiometry (DXA) and HGS using a dynamometer. Results In girls, HGS was positively associated with higher BMD, even after the adjustments, by arms [β = 0.006; p < 0.001], legs [β = 0.014; p < 0.001], pelvis [β = 0.019; p < 0.001], trunk [β = 0.013; p < 0.001], spine [β = 0.013; p = 0.008], and total body [β = 0.009; p < 0.001]. The same occurred in the boys, even after the adjustments a positive relationship was observed, whereas higher HGS was related to greater BMD in arms [β = 0.006; p < 0.001], legs [β = 0.017; p < 0.001], pelvis [β = 0.014; p < 0.001], trunk [β = 0.009; p < 0.001], spine [β = 0.008; p < 0.001], and total body [β = 0.007; p < 0.001]. Conclusion HGS was positively associated to BMD in boys and girls, regardless of age, PHV, PLST, and PFM.